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An Aspartame Safety Update

Greg Szymanski

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By Dr. Betty Martini, D.Hum.

Mission Possible International

9270 River Club Parkway

Duluth, Georgia 30097

Telephone: 770-242-2599


Web Site:

Posted: 06 June 2008

Aspartame (NutraSweet/Equal/Spoonful/E951/Canderel) is an additive excitoneurotoxic carcinogenic drug that interacts with virtually all drugs and vaccines. It was known that it would cancer before it was ever approved.

On August 1, l985 the FDA's own toxicologist, Dr. Adrian Gross, told Congress at least one of Searle's studies "has established beyond ANY REASONABLE DOUBT that aspartame is capable of inducing brain tumors in experimental animals and that this predisposition of it is of extremely high significance. ... In view of these indications that the cancer causing potential of aspartame is a matter that had been established WAY BEYOND ANY REASONABLE DOUBT, one can ask: What is the reason for the apparent refusal by the FDA to invoke for this food additive the so-called Delaney Amendment to the Food, Drug and Cosmetic Act?"

The Delaney Amendment makes it illegal to allow any residues of cancer causing chemicals in foods. In his concluding testimony Gross asked, "Given the cancer causing potential of aspartame how would the FDA justify its position that it views a certain amount of aspartame as constituting an allowable daily intake or 'safe' level of it? Is that position in effect not equivalent to setting a 'tolerance' for this food additive and thus a violation of that law? And if the FDA itself elects to violate the law, who is left to protect the health of the public?" Congressional Record SID835:131 (August 1, l985)

From the FDA Task Force Report:

  • "Excising masses (tumors) from live animals, in some cases without histologic examination of the masses, in others without reporting them to the FDA." (Schmidt l976c, page 4 of US Senate l976b). Searle's representatives, when caught and questioned about these actions, stated that "these masses were in the head and neck areas and prevented the animals from feeding." (Buzzard 1976a)
  • [Martini: Frankly, a burglar could think of a better alibi!
  • And just how many brain tumors were excised that weren't caught?]
  • "Failure to report to the FDA all internal tumors present in the experimental rats, e.g. polyps in the uterus, ovary neoplasms as well as other lesions." (Gross l987a, page 8)
  • FDA caught Searle red-handed filtering out neoplasms, excising tumors from rats, putting the rats back in the study and when they died resurrecting them on paper.
  • But then what would you expect, as aspartame breaks down to a brain tumor agent, DKP.
  • There were so many tumors found, more mammary tumors than brain tumors, thyroid, pancreatic and testicular tumors, ovarian and uterine, etc.
  • The reason the FDA revoked the petition for approval was because of the brain tumor issue, and the fact it couldn't be proven safe. You will find the URL in this report to the current FDA Commissioner.
  • Then in 2005 the prestigious Ramazzini Study was released showing aspartame to be a multipotential carcinogen and confirming those original FDA studies. So the aspartame manufacturers with their government influence immediately began to try to rebut this study. It would have made a great movie, the things that went on. They would have been laughing in the aisles. First they called a 10 year old multifood form a huge cancer study of aspartame with 1/2 million people. The multifood form was sent out by AARP asking elderly people if they remembered what they ate in the past 12 months. Frankly, I call it the Oatmeal-brownie study, although they asked if you remembered eating strawberries in season and if you had a hysterectomy. Of the 56 questions aspartame was only mentioned "once". In that question it was really asking if you drank coffee or tea, and if so what sweetener. Otherwise, it said to go to number 27 and answer whether you take vitamins. What this form didn't ask is if you were using any of the 6000 or more products containing aspartame.
  • Here is the real report: So this report mentioned by the National Cancer Institute is BOGUS!!!!!!!!!!!!!!!!!!!
  • Now what to do? They had the European Food Safety Authority review the study, and they said the rats got cancer because they had respiratory disease. Well anyone knows that respiratory disease is the dying process. Dr. Soffritti wrote a press release on this "bizarre" statement. And everybody laughed but the EFSA did not apologize so I simply reported them to the Universal Court of Justice and some committee members links to Ajinomoto. Then one member on the committee confessed that industry pressured them to hi-jack science. They certainly owed Dr. Soffritti an apology but they simply hid their head and hoped it would blow over.
  • The fiasco went on and on. There were even complaints that too much aspartame was used.
  • So, Dr. Soffritti simply did a new study using lower doses. Guess what, even in lower doses aspartame caused cancer, of course - after all, its a carcinogen!

Here are the facts on the Ramazzini Studies:

DR. MORANDO SOFFRITTI, lead researcher on two groundbreaking long-term aspartame studies..He was recently honored at New Yorks Mt Sinai School of Medicine with the Irving J Selikoff Award For his outstanding contributions to the identification of environmental and industrial carcinogens and his promotion of independent scientific research Reviewing his two impeccable aspartame studies Dr. Soffritti explains:

The first ERF study (2005) was conducted on 1800 Sprague-Dawley rats (100-150/per sex/per group) In order to simulate daily human intake, aspartame was added to the standard rat diet in quantities of 5000, 2500, 100, 500, 20, 4, and 0 mg/Kg of body weight. Treatment of the animals began at 8 weeks of age and continued until spontaneous death. The results show that APM causes a statistically significant, dose-related increase of lymphomas/leukemias and malignant tumors of the renal pelvis in females and malignant tumors of peripheral nerves in males. These results demonstrate for the first time that APM is a carcinogenic agent, capable of inducing malignancies at various dose levels, including those lower than the current acceptable daily intake (ADI) for humans (50 mg/kg of body weight in the US, 40 mg/kg of body weight in the EU).

The second ERF study (2007) was conducted on 400 Sprague-Dawley rats (70-95/per sex/per group). In order to simulate daily human intake, aspartame was added to the standard rat diet in quantities of 100, 20, and 0 mg/Kg of body weight. Treatment of the animals began on the 12th day of fetal life until natural death. The results of the second study show an increased incidence of lymphomas/leukemias in female rats with respect to the first study. Moreover, the study shows that when lifespan exposure to APM begins during fetal life, the age at which lymphomas/leukemias develop in females is anticipated. For the first time, a statistically significant increase in mammary cancers in females was also observed in the second study. The results of this transplacental carcinogenicity bioassay not only confirm, but also reinforce the first experimental demonstration of APMs multipotential carcinogenicity.

Russell Blaylock, M.D. Neurosurteon: Author: Excitotoxins: The Taste That Kills. Lecture: The Truth About Aspartame Commenting on the Ramazzini studies, above, Dr Blaylock states: My review of the first Ramazzini Study concluded that the study was one of the best designed, comprehensive and conclusive studies done to date on the multipotential carcinogenic danger of aspartame. This second study is even more conclusive, in that it shows a dose-dependent statistically significant increase in lymphomas/leukemia in both male and female rats exposed to aspartame. These two cancers are the fastest growing cancers in people under age 30.

As to diabetes, aspartame can precipitate diabetes, simulates and aggravates diabetic retinopathy and neuropathy, destroys the optic nerve, causes diabetics to go into convulsions, interacts with insulin, and the free methyl alcohol causes them to lose limbs. Aspartame is a diabetic killer!! It also triggers an irregular heart rhythm, interacts with all cardiac medication, damages the cardiac conduction system and causes sudden death. Aspartame Disease: An Ignored Epidemic, by diabetic specialist, H. J. Roberts, M.D. See these reports on sudden death: and

A safe sweetener is Just Like Sugar, which you can get in Whole Foods or Wild Oats, made with chicory and orange peel.

Dr. Betty Martini, D.Hum.

Founder, Mission Possible World Health International

9270 River Club Parkway

Duluth, Georgia 30097



Aspartame Toxicity Center:

Aspartame Documentary: Sweet Misery: A Poisoned World,

An Aspartame Safety Update,on-nutritionwise-060508-s1.article

June 5, 2008

By KAREN COLLINS Q: What is the latest understanding of the safety of aspartame?

A: In one of the most recent studies, researchers fed various doses of aspartame (marketed as NutraSweet and Equal) to rats and found that the highest dose increased risk of leukemia, lymphoma and breast cancer. However, that dose (100 milligrams per kilogram of body weight) would equal 36 cans of diet soda a day for someone who weighs 150 pounds, and 12 cans a day for a 50-pound child. Some people are worried about a tendency in that study for increased risk at even 20 mg per kg of body weight, but those results were not statistically significant, which means that the slight increase could just as likely be due to chance.

A study of over half a million people by the National Cancer Institute found no cancer link with amounts of aspartame found in about 18 cans of diet soda. The upper limit of safety, called the Acceptable Daily Intake, is set at 50 mg per kg body weight in the United States. That figure corresponds to about 6 cans of diet soda per day for a 50-pound child and 18 cans for someone who weighs 150 pounds. Of course, aspartame can be found in a variety of foods. As with any part of our diet, moderation is the best policy. Most of us can make changes to our eating habits that will have much more cancer-prevention benefit than worrying about moderate use of aspartame-sweetened foods.

Q: Can diet change someone's risk of getting diabetes or is it just important for treating it?

A: A healthy lifestyle, including good eating habits, plays an important role in avoiding diabetes. If you are overweight, especially if your weight has settled around your waist, work toward a healthier weight by reducing calorie consumption and increasing activity level. Even if you're not overweight, the United States Department of Agriculture recommends at least 30 minutes (preferably 60 minutes) of daily physically activity, which is linked with lower risk of diabetes as well as other health benefits.

Limit saturated fat intake from high-fat meats and dairy products. Fruits, vegetables, whole grains and dried beans contain antioxidants that fight inflammation linked to diabetes and provide nutrients like magnesium that may be protective. These foods also provide fiber; a type of fiber in whole grains seems to improve insulin function.

Aim for at least five servings (preferably seven to 10) of fruits and vegetables daily. Also try to eat at least three to four servings of whole grains. Finally, limit sugar-sweetened drinks since preliminary evidence suggests drinking these beverages daily may increase risk of diabetes. Drinking sugar-sweetened drinks regularly certainly makes weight control more difficult, anyway. The great news is that these steps can also lower your risk of cancer.

--Karen Collins writes for American Institute for Cancer Research. Visit the Nutrition Hotline at or call (800) 843-8114 from 9 a.m. to 5 p.m., Monday through Friday ET.